To reach “elusive” communities, organizations will need to meet several important conditions for success. These include the necessary technical skills and resources to address critical health issues cost-effectively; the bonds of trust-developed through long-term field presence that forms the basis for effective work with communities; the ability to engage in rigorous testing of new methodologies; and, systems for effectively disseminating information on best practices to policy-makers and other implementing institutions. New, creative partnerships that link non-governmental organizations (NGOs), governments, community-based organizations (CBOs), other civil society actors, universities, and a host of bilateral and multilateral institutions are another prerequisite for meeting the challenge of reaching those who have been largely unaffected by the child survival and maternal health revolutions. The CORE Group meets all these conditions for success and is thus uniquely positioned to enhance the health and wellbeing of those who have been bypassed by recent child and maternal health advances. Comprised of 35 citizen supported, private voluntary, non-governmental organizations (PVOs) that work in over 140 countries, CORE Group members strengthen primary health care, often in the context of multi-sectoral development programs. Members share a common mission: to strengthen local capacity on a global scale to measurably improve the health and well-being of children and women.