On October 11th, 2012, in Amsterdam, Medicus Mundi International members, and representatives from NGOs/Academic Institutions came together to discuss the strengthening of health systems. The main question was whether it was possible to strengthen health systems and address fragility at the same time. Eleven selected country case studies were discussed in three working groups. These studies showed that it was possible to strengthen and address fragility at the same time, given proper strategies are used. The need for developing a deeper understand as health as an instrument of change was stressed, as well as the research needed to make this possible.